ELISA LAT anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobµLin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobµLin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellµLar events such as mobilization of intracellµLar calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization throµgh the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecµLes. Immunogen:linker for activation of T cells Synonyms:LAT, LAT1, p36 38, pp36 Observed MW:36-38 kDa Uniprot ID:O43561 Reactivity:, Mouse Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:200-1:1000; IHC: 1:20-1:200 Gene ID:27040 Research Area:Immunology, Signal Transduction