ELISA KEAP1 anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:9E2 Isotype:IgG2a Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CµL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resµLting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. Immunogen:kelch-like ECH-associated protein 1 Synonyms:INRF2, KIAA0132, KLHL19 Observed MW:55-70 kDa Uniprot ID:Q14145 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, WB, IF Recommended dilution:WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100 Gene ID:9817 Research Area:Cancer, Metabolism