ELISA IRF8 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Specifically binds to the upstream regµLatory region of type I IFN and IFN-inducible MHC class I genes(the interferon consensus sequence(ICS)). Plays a negative regµLatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regµLatory element, followed by cooperative binding of BATF and IRF8 and activation of genes(By similarity).
Immunogen:interferon regµLatory factor 8
Synonyms:ICSBP1
Observed MW:50kd
Uniprot ID:Q02556
Reactivity:
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:3394
Research Area:Epigenetics, Cancer, Metabolism