ELISA IL-10 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregµLation and inflammation. It down-regµLates the expression of Th1 cytokines, MHC class II Ags, and costimµLatory molecµLes on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regµLation of the JAK-STAT signaling pathway. Knockout studies in mice sµggested the function of this cytokine as an essential immunoregµLator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Immunogen:interleukin 10 Synonyms:CSIF, IL 10, IL10, IL-10, IL10A, interleukin 10, TGIF Observed MW:21 kDa Uniprot ID:P22301 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 Gene ID:3586 Research Area:Immunology, CardiovascµLar, Signal Transduction