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ELISA IL1 Beta anti-

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Quantity:100µg Purification:Protein G purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:9G5 Isotype:IgG1 Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellµLar activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Immunogen:interleukin 1, beta Synonyms:IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1?, Interleukin 1 beta, interleukin 1, beta Observed MW:35kDa Uniprot ID:P01584 Reactivity: Tested Application:ELISA, IHC, WB Recommended dilution:WB: 1:1000-1:4000; IHC: 1:50-1:500 Gene ID:3553 Research Area:Neuroscience, Immunology, CardiovascµLar, Signal Transduction

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