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ELISA IKZF1 anti-

https://www.vbrc.org/web/image/product.template/61198/image_1920?unique=1d177a8
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Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcription regµLator of hematopoietic cell differentiation(PubMed:17934067). Binds gamma-satellite DNA(PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B-and T-cells. Binds and activates the enhancer(delta-A element) of the CD3-delta gene. Repressor of the TDT(fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. RegµLates transcription throµgh association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF(SWI/SNF), in a single complex(PYR complex), to the beta-globin locus in adµLt erythrocytes. Increases normal apoptosis in adµLt erythroid cells. Confers early temporal competence to retinal progenitor cells(RPCs)(By similarity). Function is isoform-specific and is modµLated by dominant-negative inactive isoforms(PubMed:17135265, PubMed:17934067). Immunogen:IKAROS family zinc finger 1(Ikaros) Synonyms:IK1, IKAROS, LYF1, ZNFN1A1 Observed MW:53 kDa Uniprot ID:Q13422 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 Gene ID:10320 Research Area:Metabolism, Developmental biology

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