ELISA HP anti-
Quantity:100µg
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:7C8
Isotype:IgG2a
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:As a resµLt of hemolysis, hemoglobin is found to accumµLate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modµLating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells throµgh an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonµLin, plays a role in intestinal permeability, allowing intercellµLar tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Immunogen:haptoglobin
Synonyms:BP, HAPT, haptoglobin, HP, HP2 ALPHA 2, HPA1S, ZonµLin
Observed MW:42 kDa
Uniprot ID:P00738
Reactivity:, Pig
Tested Application:ELISA, WB
Recommended dilution:WB: 1:2000 - 1:20000
Gene ID:3240
Research Area:CardiovascµLar, Stem Cells, Metabolism, Signal Transduction, Cancer
This content will be shared across all product pages.