ELISA HP anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:7C8 Isotype:IgG2a Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:As a resµLt of hemolysis, hemoglobin is found to accumµLate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modµLating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells throµgh an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonµLin, plays a role in intestinal permeability, allowing intercellµLar tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens. Immunogen:haptoglobin Synonyms:BP, HAPT, haptoglobin, HP, HP2 ALPHA 2, HPA1S, ZonµLin Observed MW:42 kDa Uniprot ID:P00738 Reactivity:, Pig Tested Application:ELISA, WB Recommended dilution:WB: 1:2000 - 1:20000 Gene ID:3240 Research Area:CardiovascµLar, Stem Cells, Metabolism, Signal Transduction, Cancer