ELISA HOPX anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Atypical homeodomain protein which does not bind DNA and is required to modµLate cardiac growth and development. Acts via its interaction with SRF, thereby modµLating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
Immunogen:HOP homeobox
Synonyms:HOD, HOP, LAGY, NECC1, OB1
Observed MW:8-12kd
Uniprot ID:Q9BPY8
Reactivity:, Mouse, Rat
Tested Application:ELISA, IF, WB
Recommended dilution:WB: 1:500-1:2000; IF: 1:50-1:200
Gene ID:84525
Research Area:CardiovascµLar, Metabolism, Developmental biology