Skip to Content

ELISA HNRNPC anti-

https://www.vbrc.org/web/image/product.template/43107/image_1920?unique=10f13b7
(0 review)
Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles(PubMed:8264621). Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non-coding RNAs(lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regµLation of mRNA splicing(PubMed:25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modµLates the stability and the level of translation of bound mRNA molecµLes(PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Immunogen:heterogeneous nuclear ribonucleoprotein C(C1/C2) Synonyms:HNRPC Observed MW:32 kDa Uniprot ID:P07910 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF, FC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:3183 Research Area:Neuroscience, Metabolism

470.00 470.0 USD 470.00

470.00

Not Available For Sale

This combination does not exist.

Terms and Conditions
30-day money-back guarantee
Shipping: 2-3 Business Days