ELISA GZMB anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis. Immunogen:granzyme B Synonyms:CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, Endogenous granzyme B, Granzyme B, GZMB, HLP, SECT Observed MW:33 kDa Uniprot ID:P10144 Reactivity: Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500 Gene ID:3002 Research Area:Cancer, Immunology, Metabolism