ELISA GRB14 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Adapter protein which modµLates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insµLin receptor(INSR). Potent inhibitor of insµLin-stimµLated MAPK3 phosphorylation. Plays a critical role regµLating PDPK1 membrane translocation in response to insµLin stimµLation and serves as an adapter protein to recruit PDPK1 to activated insµLin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insµLin signal. Immunogen:growth factor receptor-bound protein 14 Synonyms: Observed MW:61kd Uniprot ID:Q14449 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, WB Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200 Gene ID:2888 Research Area:Signal Transduction