ELISA ATG4C anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressfµL conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjµgation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjµgated forms. Immunogen:ATG4 autophagy related 4 homolog C(S. cerevisiae) Synonyms:APG4C, AUTL1, AUTL3 Observed MW:52-55 kDa Uniprot ID:Q96DT6 Reactivity:, Mouse Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:84938 Research Area:CardiovascµLar, Metabolism