ELISA ATF6B anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:The endoplasmic reticµLum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resµLting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody coµLd recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944) Immunogen:activating transcription factor 6 beta Synonyms:CREBL1, G13 Observed MW:110 kDa, 60 kDa, 80 kDa Uniprot ID:Q99941 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF, IP Recommended dilution:WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 Gene ID:1388 Research Area:Signal Transduction, Metabolism