ELISA ARRDC3 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Adapter protein that plays a role in regµLating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).
Immunogen:arrestin domain containing 3
Synonyms:ARRDC3, arrestin domain containing 3, KIAA1376, TLIMP
Observed MW:46 kDa
Uniprot ID:Q96B67
Reactivity:
Tested Application:ELISA, WB, IF
Recommended dilution:WB: 1:500-1:1000; IF: 1:10-1:100
Gene ID:57561
Research Area:Metabolism