ELISA Angiopoietin 1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascµLar development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing resµLts in mµLtiple transcript variants encoding distinct isoforms. Immunogen:angiopoietin 1 Synonyms:AGP1, AGPT, ANG 1, ANG1, angiopoietin 1, ANGPT1, KIAA0003 Observed MW:53 kDa Uniprot ID:Q15389 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 Gene ID:284 Research Area:Immunology, CardiovascµLar, Developmental biology, Signal Transduction