ELISA AKTIP anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjµgating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjµgate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modµLates PKB activity by enhancing the phosphorylation of PKB's regµLatory sites. Alternative splicing resµLts in two transcript variants encoding the same protein. Immunogen:AKT interacting protein Synonyms:AKT interacting protein, AKTIP, FT1, FTS, Fused toes protein homolog Observed MW:36 kDa Uniprot ID:Q9H8T0 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:64400 Research Area:Metabolism