ELISA HSD3B7 anti-

Quantity :50µL Clone Number: Aliases:HSD3B73 beta-hydroxysteroid dehydrogenase type 7 antibody; 3 beta-hydroxysteroid dehydrogenase type VII antibody; 3-beta-HSD VII antibody; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody; C(27) 3-beta-HSD antibody; EC 1.1.1.- antibody; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase antibody; EC 1.1.1.181 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H2F3 Immunogen:Fusion protein of HSD3B7 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticµLum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. MµLtiple transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HSD3B7 Research Areas:Signal transduction