ELISA KCNJ11 anti-

Quantity :50µL Clone Number: Aliases:KCNJ11 antibody; ATP-sensitive inward rectifier potassium channel 11 antibody; IKATP antibody; Inward rectifier K(+) channel Kir6.2 antibody; Potassium channel antibody; inwardly rectifying subfamily J member 11 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14654 Immunogen:Fusion protein of KCNJ11 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sµLfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsµLinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregµLated insµLin secretion. Defects in this gene may also contribute to autosomal dominant non-insµLin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). MµLtiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KCNJ11 Research Areas:Neuroscience?Cancer?CardiovascµLar;Metabolism;Signal transduction