ELISA INO80 Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:DNA helicase INO80 antibody; hINO80 antibody; homolog of yeast INO80 antibody; INO80 antibody; INO80 complex subunit A antibody; INO80 homolog antibody; INO80_ antibody; INO80A antibody; INOC1 antibody; KIAA1259 antibody; Putative DNA helicase INO80 complex homolog 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9µLG1
Immunogen:Recombinant Chromatin-remodeling ATPase INO80 protein (1365-1495AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regµLation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). RegµLates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect throµgh transcriptional regµLation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubµLe assembly during mitosis thereby regµLating chromosome segregation cycle (PubMed:20237820).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:INO80
Research Areas:Epigenetics and Nuclear Signaling