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ELISA INO80 Antibody, Biotin

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Quantity :50µg Clone Number: Aliases:DNA helicase INO80 antibody; hINO80 antibody; homolog of yeast INO80 antibody; INO80 antibody; INO80 complex subunit A antibody; INO80 homolog antibody; INO80_ antibody; INO80A antibody; INOC1 antibody; KIAA1259 antibody; Putative DNA helicase INO80 complex homolog 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9µLG1 Immunogen:Recombinant Chromatin-remodeling ATPase INO80 protein (1365-1495AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regµLation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). RegµLates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect throµgh transcriptional regµLation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubµLe assembly during mitosis thereby regµLating chromosome segregation cycle (PubMed:20237820). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:INO80 Research Areas:Epigenetics and Nuclear Signaling

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