Skip to Content

ELISA IFIH1 Antibody, Biotin

https://www.vbrc.org/web/image/product.template/60529/image_1920?unique=1d177a8
(0 review)
Quantity :50µg Clone Number: Aliases:CADM-140 autoantigen antibody; Clinically amyopathic dermatomyositis autoantigen 140 kDa antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide antibody; DEAD/H box polypeptide antibody; Helicard antibody; Helicase with 2 CARD domains antibody; Hlcd antibody; IDDM 19 antibody; IDDM19 antibody; IFIH 1 antibody; Ifih1 antibody; IFIH1_ antibody; Interferon induced helicase C domain containing protein 1 antibody; interferon induced with helicase C domain 1 antibody; Interferon induced with helicase C domain protein 1 antibody; Interferon-induced helicase C domain-containing protein 1 antibody; Interferon-induced with helicase C domain protein 1 antibody; MDA 5 antibody; MDA-5 antibody; Melanoma differentiation associated protein 5 antibody; Melanoma differentiation-associated gene 5 antibody; Melanoma differentiation-associated protein 5 antibody; MGC133047 antibody; Murabutide down regµLated protein antibody; Murabutide down-regµLated protein antibody; RH 116 antibody; RH116 antibody; RIG I like receptor 2 antibody; RLR 2 antibody; RNA helicase DEAD box protein 116 antibody; RNA helicase-DEAD box protein 116 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BYX4 Immunogen:Recombinant Interferon-induced helicase C domain-containing protein 1 protein (700-1025AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking 2\'-O-methylation at their 5\' cap and long-dsRNA (>1 kb in length). Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regµLatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs); IFN-alpha and IFN-beta. Responsible for detecting the Picornaviridae family members such as encephalomyocarditis virus (EMCV) and mengo encephalomyocarditis virus (ENMG). Can also detect other viruses such as dengue virus (DENV), west Nile virus (WNV), and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome, such as vaccinia virus. Plays an important role in amplifying innate immune signaling throµgh recognition of RNA metabolites that are produced during virus infection by ribonuclease L (RNase L). May play an important role in enhancing natural killer cell function and may be involved in growth inhibition and apoptosis in several tumor cell lines. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IFIH1 Research Areas:Epigenetics and Nuclear Signaling; Immunology; Microbiology

431.60 431.6 USD 431.60

431.60

Not Available For Sale

This combination does not exist.

Terms and Conditions
30-day money-back guarantee
Shipping: 2-3 Business Days