ELISA HIPK3 anti-
Quantity :50µg
Clone Number:
Aliases:Androgen receptor interacting nuclear protein kinase antibody; Androgen receptor-interacting nuclear protein kinase antibody; ANPK antibody; DYRK6 antibody; Fas interacting serine/threonine protein kinase antibody; Fas-interacting serine/threonine-protein kinase antibody; FIST antibody; FIST3 antibody; Hipk3 antibody; HIPK3_ antibody; homeodomain interacting protein kinase 3 antibody; Homeodomain-interacting protein kinase 3 antibody; Homolog of protein kinase YAK1 antibody; PKY antibody; RP24 297H17.5 antibody; YAK1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9H422
Immunogen:Recombinant Homeodomain-interacting protein kinase 3 protein (841-1130AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Background:Serine/threonine-protein kinase involved in transcription regµLation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regµLate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimµLation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HIPK3
Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Signal transduction