ELISA IFT57 anti-
Quantity :50µL
Clone Number:
Aliases:CDNA FLJ10147 fis clone HEMBA1003369 antibody; Dermal papilla derived protein 8 antibody; Dermal papilla-derived protein 8 antibody; DERP 8 antibody; DERP8 antibody; Esrrbl 1 antibody; Esrrbl1 antibody; ESRRBL1 protein antibody; Estrogen related receptor beta like 1 antibody; Estrogen related receptor beta like protein 1 antibody; Estrogen-related receptor beta-like protein 1 antibody; FLJ10147 antibody; Hip1 Interacting protein antibody; HIP1 interacting protein HIPPI antibody; Hip1 protein interactor antibody; HIP1-interacting protein antibody; HIPPI antibody; Huntingtin interacting protein 1 interacting protein antibody; Huntingtin interacting protein 1 protein interactor antibody; IFT 57 antibody; ift57 antibody; IFT57_ antibody; Intraflagellar transport 57 homolog (Chlamydomonas) antibody; Intraflagellar transport 57 homolog antibody; Intraflagellar transport protein 57 homolog antibody; MHS4R2 antibody; Vestrogen related receptor beta like 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9NWB7
Immunogen:Recombinant Intraflagellar transport protein 57 homolog protein (170-429AA)
Raised in:Rabbit
Reactivity:, Mouse
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200
Background:Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5\\\'-AAAGACATG-3\\\' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, sµggesting that it may act as a transcription regµLator; however the relevance of such function remains unclear.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IFT57
Research Areas:Neuroscience