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ELISA HSD3B7 Antibody, HRP

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Quantity :50µg Clone Number: Aliases:HSD3B73 beta-hydroxysteroid dehydrogenase type 7 antibody; 3 beta-hydroxysteroid dehydrogenase type VII antibody; 3-beta-HSD VII antibody; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody; C(27) 3-beta-HSD antibody; EC 1.1.1.- antibody; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase antibody; EC 1.1.1.181 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H2F3 Immunogen:Recombinant 3 beta-hydroxysteroid dehydrogenase type 7 protein (131-197AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HSD3B7 Research Areas:Signal transduction

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