ELISA ARRDC3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ARRDC3 antibody; KIAA1376 antibody; Arrestin domain-containing protein 3 antibody; TBP-2-like inducible membrane protein antibody; TLIMP antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96B67 Immunogen:Recombinant Arrestin domain-containing protein 3 protein (1-270AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Adapter protein that plays a role in regµLating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARRDC3 Research Areas:Cell biology