ELISA ARRB1 anti-

Quantity :50µL Clone Number: Aliases:ARB1 antibody; ARR1 antibody; ARRB1 antibody; ARRB1_ antibody; Arrestin 2 antibody; Arrestin beta 1 antibody; Arrestin beta-1 antibody; Beta-arrestin-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P49407 Immunogen:Synthetic peptide of ARRB1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 Background:Members of arrestin/beta-arrestin protein family are thoµght to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellµLar responses to stimµLi such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regµLating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARRB1 Research Areas:Neuroscience;Signal transduction