ELISA AXIN1 anti-

Quantity :50µL Clone Number: Aliases:axin 1 Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15169 Immunogen:Synthetic peptide of AXIN1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:This gene encodes a cytoplasmic protein which contains a regµLation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regµLator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellµLar carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medµLlablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AXIN1 Research Areas:Cell biology;Tags & Cell Markers;Signal transduction?Stem cells