ELISA HIPK1 Antibody, FITC

Quantity :50µg Clone Number: Aliases:Hipk 1 antibody; Hipk1 antibody; HIPK1_ antibody; Homeodomain interacting protein kinase 1 antibody; Homeodomain interacting protein kinase 1 like protein antibody; Homeodomain-interacting protein kinase 1 antibody; Myak antibody; Nbak 2 antibody; Nbak2 antibody; Nuclear body associated kinase 2 antibody; Nuclear body associated kinase 2b antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86Z02 Immunogen:Recombinant Homeodomain-interacting protein kinase 1 protein (1007-1151AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Serine/threonine-protein kinase involved in transcription regµLation and TNF-mediated cellµLar apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimµLi, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regµLation of eye Quantity, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HIPK1 Research Areas:Epigenetics and Nuclear Signaling; Signal transduction