ELISA ARPIN anti-
Quantity :50µg
Clone Number:
Aliases:2610034B18Rik antibody; Actin related protein 2/3 complex inhibitor antibody; Arp2/3 inhibition protein antibody; ARPIN antibody; C15orf38 antibody; Chromosome 15 open reading frame 38 antibody; CO038_ antibody; Hypothetical protein LOC348110 antibody; MGC61550 antibody; RIKEN cDNA 2610034B18 antibody; UPF0552 protein C15orf38 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q7Z6K5
Immunogen:Recombinant Arpin protein (1-226AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Background:RegµLates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimµLates actin polymerization throµgh the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ARPIN
Research Areas:Cell biology