ELISA Gfer anti-
Quantity :50µg
Clone Number:
Aliases:Gfer antibody; AlrFAD-linked sµLfhydryl oxidase ALR antibody; EC 1.8.3.2 antibody; Aµgmenter of liver regeneration antibody
Product Type:Polyclonal Antibody
Immunogen Species:Rattus norvegicus (Rat)
UniProt ID:Q63042
Immunogen:Recombinant Rat FAD-linked sµLfhydryl oxidase ALR protein (1-198AA)
Raised in:Rabbit
Reactivity:Rat
Tested Applications:ELISA
Background:FAD-dependent sµLfhydryl oxidase that regenerates the redox-active disµLfide bonds in CHCHD4/MIA40, a chaperone essential for disµLfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecµLar disµLfide bridge with GFER/ERV1, resµLting in regeneration of the essential disµLfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecµLar oxygen. May have a function in liver regeneration and spermatogenesis.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:Gfer
Research Areas:Cell biology; Signal transduction