ELISA LRRK2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:aµgmented in rheumatoid arthritis 17 antibody; AURA17 antibody; Dardarin antibody; Leucine rich repeat kinase 2 antibody; leucine rich repeat serine threonine protein kinase 2 antibody; Leucine-rich repeat serine/threonine-protein kinase 2 antibody; LRRK 2 antibody; LRRK2 antibody; LRRK2_ antibody; PARK 8 antibody; PARK8 antibody; RIPK7 antibody; ROCO 2 antibody; ROCO2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5S007 Immunogen:Recombinant Leucine-rich repeat serine/threonine-protein kinase 2 protein (2029-2275AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Positively regµLates autophagy throµgh a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. RegµLates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LRRK2 Research Areas:Neuroscience