ELISA LATS2 anti-

Quantity :50µL Clone Number: Aliases:FLJ13161 antibody; Kinase phosphorylated during mitosis protein antibody; KPM antibody; Large tumor suppressor homolog 2 antibody; Large tumor suppressor homolog 2 Drosophila antibody; Large tumor suppressor kinase 2 antibody; LATS large tumor suppressor Drosophila homolog 2 antibody; LATS large tumor suppressor homolog 2 antibody; Lats2 antibody; LATS2_ antibody; Serine/threonine kinase kpm antibody; Serine/threonine protein kinase kpm antibody; Serine/threonine-protein kinase kpm antibody; Serine/threonine-protein kinase LATS2 antibody; Warts like kinase antibody; Warts-like kinase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NRM7 Immunogen:Synthetic peptide of LATS2 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumµLation of gamma-tubµLin and spindle formation at the onset of mitosis. It also interacts with a negative regµLator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LATS2 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Signal transduction