ELISA KLF1 Antibody, FITC

Quantity :50µg Clone Number: Aliases:CDAN4 antibody; EKLF antibody; EKLF PEN antibody; Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) antibody; Erythroid krueppel-like transcription factor antibody; Erythroid Kruppel like factor antibody; Erythroid specific transcription factor EKLF antibody; HBFQTL6 antibody; erythroid-specific transcription factor EKLF mRNA complete cds antibody; INLU antibody; Klf1 antibody; KLF1_ antibody; Krueppel-like factor 1 antibody; Kruppel like factor 1 (erythroid) antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13351 Immunogen:Recombinant Krueppel-like factor 1 protein (1-362AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Transcription regµLator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regµLator of fetal-to-adµLt globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adµLts, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KLF1 Research Areas:Epigenetics and Nuclear Signaling