ELISA ACY1 anti-

Quantity :50µL Clone Number: Aliases:ACY 1 antibody; ACY-1 antibody; Acy1 antibody; ACY1_ antibody; ACY1D antibody; ACYLASE antibody; Acylase I antibody; Aminoacylase 1 antibody; Aminoacylase-1 antibody; EC 3.5.1.14 antibody; epididymis secretory protein Li 5 antibody; HEL-S-5 antibody; N acyl L amino acid amidohydrolase antibody; N-acyl-L-amino-acid amidohydrolase antibody; OTTHUMP00000212459 antibody; OTTHUMP00000212462 antibody; OTTHUMP00000212463 antibody; OTTHUMP00000212464 antibody; OTTHUMP00000212465 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q03154 Immunogen:Fusion protein of ACY1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 Background:This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postµLated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene resµLts in mµLtiple transcript variants. Read-throµgh transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ACY1 Research Areas:Metabolism;Signal transduction