ELISA ITPR1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:4 antibody; 5-trisphosphate receptor antibody; 5-trisphosphate receptor type 1 antibody; DKFZp313E1334 antibody; DKFZp313N1434 antibody; inositol 1 4 5 triphosphate receptor type 1 antibody; Inositol 1 4 5 trisphosphate Receptor Type 1 antibody; Inositol 1 antibody; InsP3R1 antibody; IP3 antibody; IP3 receptor antibody; IP3 receptor isoform 1 antibody; IP3R 1 antibody; IP3R antibody; IP3R1 antibody; ITPR 1 antibody; Itpr1 antibody; ITPR1_ antibody; SCA15 antibody; SCA16 antibody; SCA29 antibody; Type 1 inositol 1 4 5 trisphosphate receptor antibody; Type 1 inositol 1 antibody; Type 1 InsP3 receptor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14643 Immunogen:Recombinant Inositol 1,4,5-trisphosphate receptor type 1 protein (1707-1966AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:IntracellµLar channel that mediates calcium release from the endoplasmic reticµLum following stimµLation by inositol 1,4,5-trisphosphate (PubMed:27108797). Involved in the regµLation of epithelial secretion of electrolytes and fluid throµgh the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ITPR1 Research Areas:Cancer; Metabolism; Signal transduction