ELISA KCNMA1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:subfamily M subunit alpha-1 antibody; BK channel antibody; BKCA alpha antibody; BKCA alpha subunit antibody; BKTM antibody; Calcium-activated potassium channel antibody; Calcium-activated potassium channel subunit alpha-1 antibody; Drosophila slowpoke like antibody; hSlo antibody; K(VCA)alpha antibody; KCa1.1 antibody; KCMA1_ antibody; KCNMA antibody; KCNMA1 antibody; Maxi K channel antibody; Maxi Potassium channel alpha antibody; MaxiK antibody; SAKCA antibody; SLO alpha antibody; SLO antibody; Slo homolog antibody; Slo-alpha antibody; Slo1 antibody; Slowpoke homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q12791 Immunogen:Recombinant Calcium-activated potassium channel subunit alpha-1 protein (1-86AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regµLation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regµLation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticµLum, regµLates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modµLating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KCNMA1 Research Areas:Others