ELISA KIF14 anti-

Quantity :50µg Clone Number: Aliases:KIAA0042 antibody; KIF 14 antibody; KIF14 antibody; KIF14_ antibody; Kinesin Family Member 14 antibody; Kinesin like protein KIF14 antibody; Kinesin-like protein KIF14 antibody; MGC142302 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15058 Immunogen:Recombinant Kinesin-like protein KIF14 protein (261-531AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:MicrotubµLe motor protein that binds to microtubµLes with high affinity throµgh each tubµLin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody throµgh its interaction with PRC1 and CIT respectively (PubMed:16431929). RegµLates cell growth throµgh regµLation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts throµgh SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resµLting in positive regµLation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regµLates the cerebellar, cerebral cortex and olfactory bµLb development throµgh regµLation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). RegµLates cell spreading, focal adhesion dynamics, and cell migration throµgh its interaction with RADIL resµLting in regµLation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubµLes (PubMed:23209302). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KIF14 Research Areas:Tags & Cell Markers; Signal transduction