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ELISA ATXN7L3 Antibody, Biotin

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Quantity :50µg Clone Number: Aliases:AT7L3_ antibody; Ataxin 7 like 3 antibody; Ataxin 7 like protein 3 antibody; Ataxin-7-like protein 3 antibody; atxn7l3 antibody; SAGA associated factor 11 homolog antibody; SAGA-associated factor 11 homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14CW9 Immunogen:Recombinant Ataxin-7-like protein 3 protein (51-347AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of the transcription regµLatory histone acetylation (HAT) complex SAGA, a mµLtiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATXN7L3 Research Areas:Epigenetics and Nuclear Signaling; Cell biology

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