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ELISA HSP90AB1 (Ab-254) anti-

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Quantity :100µL Clone Number: Aliases:90 kda heat shock protein beta HSP90 beta antibody; D6S182 antibody; FLJ26984 antibody; Heat shock 84 kDa antibody; Heat shock 90kD protein 1; beta antibody; Heat shock 90kDa protein 1 beta antibody; Heat shock protein 90 alpha family class B member 1 antibody; Heat shock protein 90 kDa antibody; Heat shock protein 90kDa alpha (cytosolic) class B member 1 antibody; Heat shock protein 90kDa alpha family class B member 1 antibody; Heat shock protein beta antibody; Heat shock protein HSP 90 beta antibody; Heat shock protein HSP 90-beta antibody; HS90B_ antibody; HSP 84 antibody; HSP 90 antibody; HSP 90 b antibody; HSP 90b antibody; HSP84 antibody; HSP90 BETA antibody; hsp90ab1 antibody; HSP90B antibody; HSPC2 antibody; HSPCB antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P08238 Immunogen:SyntheQuantityd non-phosphopeptide derived from HSP90B around the phosphorylation site of serine 254 (V-G-S(p)-D-E). Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 Background:MolecµLar chaperone that promotes the maturation, structural maintenance and proper regµLation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modµLate its substrate recognition, ATPase cycle and chaperone function. Lothar Goretzki, AACR Meeting Abstracts, Apr 2006; 2006: 468. Jean-Fran?ois Louvion, Mol. Biol. Cell, Nov 1998; 9: 3071. Angelika Lueking, Mol. Cell. Proteomics, Dec 2003; 2: 1342. Jason Fontana Circ, Res., May 2002; 90: 866. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HSP90AB1 Research Areas:Signal transduction

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