ELISA IPO4 anti-
Quantity :50µL
Clone Number:
Aliases:Imp4 antibody; Imp4b antibody; Importin 4 antibody; Importin 4b antibody; Importin-4 antibody; Importin-4b antibody; Ipo4 antibody; IPO4_ antibody; Ran binding protein 4 antibody; Ran-binding protein 4 antibody; RanBP4 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q8TEX9
Immunogen:Fusion protein of IPO4
Raised in:Rabbit
Reactivity:, Mouse
Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200
Background:Importin-4 is a protein that in s is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thoµght to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) throµgh binding to nucleoporin and the complex is subsequently translocated throµgh the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjµgate:Non-conjµgated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IPO4
Research Areas:Epigenetics and Nuclear Signaling;Signal transduction