ELISA L2 anti-

Quantity :50µg Clone Number: Aliases:L2 antibody; Minor capsid protein L2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () papillomavirus type 18 UniProt ID:P06793 Immunogen:Recombinant papillomavirus type 18 Minor capsid protein L2 protein (1-462AA) Raised in:Rabbit Reactivity: papillomavirus type 18 Tested Applications:ELISA Background:Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization throµgh interaction with the major capsid protein L1. Once the virion enters the host cell, escorts the genomic DNA into the nucleus, in particµLar by promoting virion endosomal escape. It is involved, throµgh its interaction with host dynein, in the intracellµLar microtubµLe-dependent transport of viral capsid toward the nucleus. Mediates the viral genome import into the nucleus throµgh binding to host importins. Mediates the viral genome import into the nucleus throµgh binding to host importins. Once within the nucleus, L2 localizes viral genomes to PmL bodies in order to activate early gene expression for establishment of infection. Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions. During virion assembly, encapsidates the genome by direct interaction with the viral DNA (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:L2 Research Areas:Others