ELISA AC1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:AC1 antibody; AL1 antibody; Replication-associated protein antibody; Rep antibody; EC 2.7.7.- antibody; EC 3.1.21.- antibody; 40.4 kDa protein antibody; Protein AC1 antibody; Protein AL1 antibody Product Type:Polyclonal Antibody Immunogen Species:African cassava mosaic virus (isolate West Kenyan 844) (ACMV) (Cassava latent virus (isolate West Kenyan 844)) UniProt ID:P14982 Immunogen:Recombinant African cassava mosaic virus Replication-associated protein (1-358AA) Raised in:Rabbit Reactivity:African cassava mosaic virus Tested Applications:ELISA Background:Essential for the replication of viral ssDNA. The closed circµLar ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5\'-TAATATTAC-3\' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5\'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3\'-OH that serves as a primer for the cellµLar DNA polymerase. The polymerase syntheQuantitys the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circµLar single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AC1 Research Areas:Others