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ELISA IFNT1 Antibody, HRP

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Quantity :50µg Clone Number: Aliases:IFNT1 antibody; Interferon tau-1 antibody; IFN-tau-1 antibody; Antiluteolysin antibody; Trophoblast antiluteolytic protein antibody; Trophoblast protein 1 antibody; TP-1 antibody; Trophoblastin antibody Product Type:Polyclonal Antibody Immunogen Species:Bos taurus (Bovine) UniProt ID:P15696 Immunogen:Recombinant Bovine Interferon tau-1 protein (24-195AA) Raised in:Rabbit Reactivity:Bovine Tested Applications:ELISA Background:Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This resµLts in the suppression of the pµLsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimµLates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particµLarly high antiviral and antiproliferative potency concurrently with particµLar weak cytotoxicity, high antiluteolytic activity and immunomodµLatory properties. In contrast with other IFNs, IFN-tau is not virally inducible. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IFNT1 Research Areas:Others

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