ELISA IFNT1 Antibody, HRP
Quantity :50µg
Clone Number:
Aliases:IFNT1 antibody; Interferon tau-1 antibody; IFN-tau-1 antibody; Antiluteolysin antibody; Trophoblast antiluteolytic protein antibody; Trophoblast protein 1 antibody; TP-1 antibody; Trophoblastin antibody
Product Type:Polyclonal Antibody
Immunogen Species:Bos taurus (Bovine)
UniProt ID:P15696
Immunogen:Recombinant Bovine Interferon tau-1 protein (24-195AA)
Raised in:Rabbit
Reactivity:Bovine
Tested Applications:ELISA
Background:Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This resµLts in the suppression of the pµLsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimµLates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particµLarly high antiviral and antiproliferative potency concurrently with particµLar weak cytotoxicity, high antiluteolytic activity and immunomodµLatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:HRP
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IFNT1
Research Areas:Others