ELISA KCNQ4 anti-

Quantity :50µL Clone Number: Aliases:DFNA 2 antibody; DFNA2 antibody; KCNQ 4 antibody; Kcnq4 antibody; KCNQ4_ antibody; KQT like 4 antibody; KQT-like 4 antibody; KV7.4 antibody; Potassium channel KQT like 4 antibody; Potassium channel subunit alpha KvLQT4 antibody; Potassium voltage gated channel KQT like protein 4 antibody; Potassium voltage gated channel KQT like subfamily member 4 antibody; Potassium voltage gated channel subfamily KQT member 4 antibody; Potassium voltage-gated channel subfamily KQT member 4 antibody; Voltage gated potassium channel subunit Kv7.4 antibody; Voltage-gated potassium channel subunit Kv7.4 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P56696 Immunogen:Synthetic peptide of KCNQ4 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 Background:The protein encoded by this gene forms a potassium channel that is thoµght to play a critical role in the regµLation of neuronal excitability, particµLarly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convµLsant drµg. The encoded protein can form a homomµLtimeric potassium channel or possibly a heteromµLtimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KCNQ4 Research Areas:Neuroscience