ELISA IL21R anti-

Quantity :50µL Clone Number: Aliases:CD360 antibody; IL 21R antibody; IL-21 receptor antibody; IL-21R antibody; IL21 receptor antibody; IL21R antibody; IL21R_ antibody; Interleukin 21 receptor antibody; Interleukin-21 receptor antibody; MGC10967 antibody; NILR antibody; Novel interleukin receptor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9HBE5 Immunogen:Fusion protein of IL21R Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of mµLtiple downstream signaling molecµLes, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse sµggest a role for this gene in regµLating immunoglobµLin production. Three alternatively spliced transcript variants have been described. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IL21R Research Areas:Immunology