ELISA ASCC1 anti-

Quantity :50µL Clone Number: Aliases:Activating signal cointegrator 1 complex subunit 1 antibody; ASC-1 complex subunit p50 antibody; ASC1 complex subunit p50 antibody; ASC1p50 antibody; ASCC1 antibody; ASCC1_ antibody; CGI 18 antibody; RP11-150D20.4 antibody; Trip4 complex subunit p50 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N9N2 Immunogen:Fusion protein of ASCC1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by mµLtiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding mµLtiple isoforms have been observed for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ASCC1 Research Areas:Signal transduction