ELISA LTK anti-

Quantity :100µL Clone Number: Aliases:Leukocyte receptor tyrosine kinase antibody; Leukocyte tyrosine kinase antibody; Leukocyte tyrosine kinase receptor antibody; Ltk antibody; LTK_ antibody; Protein tyrosine kinase 1 antibody; TYK 1 antibody; TYK1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P29376 Immunogen:SyntheQuantityd peptide derived from internal of LTK. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellµLar region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regµLation of the secretory pathway involving endoplasmic reticµLum (ER) export sites (ERESs) and ER to Golgi transport. Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993). Krolewski J.J., EMBO J. 10:2911-2919(1991). Maru Y., Oncogene Res. 5:199-204(1990). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LTK Research Areas:Metabolism;Signal transduction