ELISA HIST1H2BB anti-

Quantity :100µL Clone Number: Aliases:HIST1H2BB antibody; H2BFFHistone H2B type 1-B antibody; Histone H2B.1 antibody; Histone H2B.f antibody; H2B/f antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P33778 Immunogen:Peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from H2B. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellµLar machineries which require DNA as a template. Histones thereby play a central role in transcription regµLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regµLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Borchert GM,et al. (2010) PLoS One.5(7):e11641. Pennini ME,et al.(2010) PLoS Pathog.6(7):e1000995. Lu C,et al. (2010) Sci China Life Sci.53(6):663-8. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HIST1H2BB Research Areas:Others