ELISA AKAP10 anti-

Quantity :100µL Clone Number: Aliases:AKAP10A-kinase anchor protein 10 antibody; mitochondrial antibody; AKAP-10 antibody; Dual specificity A kinase-anchoring protein 2 antibody; D-AKAP-2 antibody; Protein kinase A-anchoring protein 10 antibody; PRKA10 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43572 Immunogen:SyntheQuantityd peptide derived from Internal of AKAP10. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Differentially targeted protein that binds to type I and II regµLatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Althoµgh the physiological relevance between PKA and AKAPS with mitochondria is not fµLly understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling mµLtiprotein complexes. With its RGS domain, it coµLd lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase By similarity. Wang L., Proc. Natl. Acad. Sci. U.S.A. 98:3220-3225(2001). Chatterjee T.K., Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AKAP10 Research Areas:Signal transduction