ELISA ITGB3 (Ab-785) anti-
Quantity :100µL
Clone Number:
Aliases:BDPLT16 antibody; BDPLT2 antibody; CD 61 antibody; CD61 antibody; CD61 antigen antibody; GP3A antibody; GPIIIa antibody; GT antibody; HPA 1 antibody; HPA 4 antibody; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody; Integrin beta chain beta 3 antibody; Integrin beta-3 antibody; ITB3_ antibody; ITG B3 antibody; ITGB 3 antibody; ITGB3 antibody; NAIT antibody; platelet fibrinogen receptor antibody; Platelet fibrinogen receptor beta subunit antibody; Platelet fibrinogen receptor, beta subunit antibody; Platelet glycoprotein IIIa antibody; Platelet glycoprotein IIIa precursor antibody; Platelet membrane glycoprotein IIIa antibody; PTP antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P05106
Immunogen:Peptide sequence around aa.783~787 (I-T-Y-R-G) derived from Integrin B3/ITGB3.
Raised in:Rabbit
Reactivity:, Mouse
Tested Applications:ELISA, WB; WB:1:500-1:1000
Background:
The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecµLe receptors that share a common heterotrimeric structure with a and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct a subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can resµLt from defects in the genes for either the Itg-a2B or the Itg-Beta3 subunit
Sujoy Bhattacharya, et al. (2006) Biochem J. Aµgust 1; 397(Pt 3): 437
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conjµgate:Non-conjµgated
Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ITGB3
Research Areas:CardiovascµLar;Immunology;Signal transduction