ELISA ITGB5 anti-

Quantity :50µL Clone Number: Aliases:FLJ26658 antibody; Integrin beta-5 antibody; Integrin subunit beta 5 antibody; integrin, beta 5 antibody; ITB5_ antibody; Itgb5 antibody; Testis secretory sperm-binding protein Li 217p antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P18084 Immunogen:Fusion protein of ITGB5 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100 Background:Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellµLar matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellµLar adhesion molecµLes (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ITGB5 Research Areas:Signal transduction